The main policy landscape of LIFE CONCERT REACH is the EU chemicals regulation, the so-called REACH regulation, which in practice compels the industry to assess the safety of the chemicals it produces or imports.
Extraction and evaluation of data
Extraction and evaluation of data in the dossier preparation of registered substances from AMBIT and ECHA dossiers.
Upgrading existing software
Upgrading of VEGA and ToxRead with new models/modules.
Upgrading of weight-of-evidence algorithm for integrating data from different sources and implementation into ToxWeight software.
Developing of a web-based gateway to guide users to integrate data for their optimal use for substance evaluation from VEGA (https://www.vegahub.eu/), AMBIT (https://ambitlri.ideaconsult.net) and Danish (Q)SAR Database (http://qsar.food.dtu.dk/).
Evaluation of the suitability of computational tools for modelling REACH endpoints.
Evaluation of the project impact
To evaluate the impact of the project, specifically on the improved access, usability and compliance with IUCLID scheme of NTMs. The socio-economic impact of the results of LIFE CONCERT REACH will be also evaluated. Benefits and costs will be addressed.
Communication and dissemination
A wide range of strategies, including a written plan, the website, workshops, activities towards industry or regulatory bodies, training, scientific dissemination, will be adopted.
PROJECT ACTIVITIES WILL
Supporting the REACH Regulation by exploiting hazard information on substances.
Facilitating the dialogue between regulators and industry, through the development of a unique platform.
Covering a much wider list of properties than the currently available models, through the integration of data as in AMBIT , and model as in VEGA.
Developing freely available tools for grouping and read-across with easy and user-friendly interfaces.
To facilitate assessors of substances of REACH.
To integrate the results of read-across and in silico models (weight-of-evidence approach).